It's not about the Xs and Os, it's about the Jimmys and Joes.

And the difference between Josh Allen and Case Keenum is as massive as the difference between Alfredo's Pizza Cafe and Pizza by Alfredo.

That's why Buffalo Bills fans are nervous about the possibility of playing the 7-1 Minnesota Vikings without Allen, who missed his second practice of the week on Thursday as he deals with a right elbow injury.

Many have speculated that Allen will miss the game on Sunday, which if true, would put Case Keenum in line to start against his former team.

By the way, I promise I won't mention the fact that he'd be throwing to Stefon Diggs, with whom he co-authored an iconic NFL moment playing for Minnesota because you'll hear that a million times from here to Sunday. But he will.

In all seriousness, though, the conversation will mainly center around Keenum if Allen can't go. After all, he's the backup quarterback.

But I am more intrigued about offensive coordinator Ken Dorsey and what gameplan he's able to put together if he's forced to play the backup quarterback.

After all, it's clear that the Bills won't be playing the same kind of offense if Keenum is under center. Simply put, Allen can do things Keenum can't, and betting on such a pass-happy approach would probably spell trouble for Dorsey's offense.

The same goes for asking Keenum to extend broken plays and make alien-like throws on the move while changing arm slots or casually hurdling a defender to pick up the first down scrambling.

While a lot of that is Allen being Allen, it's undeniable that the offensive design ensures he can do it consistently.

With Keenum though, the emphasis will likely be on playing smart football.

You know, the old-school game manager approach with a healthy dosage of ground and pound. Expect the Bills to get fullback Reggie Gillman involved early and often as he opens up plenty of options in the running game.

Also, Buffalo could use a lot of 12 personnel (1 running back, 2 tight ends) to ensure they can run in early downs. The Chiefs game was a great example of this as described by The Athletic's Nate Tice after Week 8:

"In Week 6 against the Chiefs, the Bills used more 12 personnel on first and second downs (seven snaps) than they had over the previous five weeks combined (five snaps). They averaged .26 EPA per play out of that personnel grouping."

Later in that article, Tice adds:

"Perhaps you’ve noticed that all of the efficient run plays above came on different run concepts, which will give opposing defensive coaches additional things to game plan for. It’s another tool in the Bills’ toolbox as defenses try to hunker down on tendencies as the season goes along."

The Bills are still trying to figure out the running game but 2 of their top 3 rushing performances per DVOA have come in the past couple of weeks.

In the biggest challenge of his play-calling career, can Dorsey make up for not having his unicorn QB with a strong game plan and great play design? If so, get ready for him to get all of the national media ovations available.

So far, the transition from Brian Daboll's offense to Dorsey's has been a smooth one. But this is the perfect chance for the OC to put his stamp on the team in his first year as a play-caller.

While Keenum will receive most of the attention heading into gameday, Dorsey is definitely the guy I'll be keeping an eye on come Sunday.

Featured image via George Walker IV / USA TODAY NETWORK