The NFL got it right when it scheduled the Buffalo Bills‘ match-up versus the Super Bowl Champions for the league’s Kickoff game. On one side, the star-studded L.A. Rams. On the other, a team everyone wanted to see one more drive from seeking immediate redemption.

The Bills, despite being the road team for this heavyweight clash, are 1.5-point favorites to win. That might grow in the next few weeks depending on how the latest news out of Los Angeles goes as the Rams might be without one of its starting receivers.

Van Jefferson – who’s expected to take on a bigger role after breaking 50 receptions for the first time in his career last season – is in question for Week 1.

The Rams are calling it a “knee tweak,” and have been very optimistic about the receiver’s health.

The expectation is for Jefferson to return in a “few weeks” per Sean McVay. That will likely keep him out for most of the preseason and his availability for the Bills is in question.

While the surgery has been labeled as a minor one, expect this to become a major storyline heading into the season opener. After all, with Robert Woods and Odell Beckham Jr. out of the Rams, Jefferson is one of their projected starters.

Buffalo will still face a tough challenge in Cooper Kupp and Allen Robinson, but the game plan would dramatically change without Matthew Stafford’s WR3. It gives the Bills’ proven defensive backfield way more options to handle the Rams’ top two targets.

Featured image via Rich Barnes-USA TODAY Sports