NASHVILLE — The Tennessee Titans (2-2) and Indianapolis Colts (2-2) will kick off an important divisional game on Sunday at 12 p.m. CST with hopes of rising to the top of the AFC south.

While the game is headlined by the returns of Colts running back Jonathan Taylor and Titans rookie offensive lineman Peter Skoronski, both teams will be without some key starters for the match up.

Here’s a full look at the six Titans players that are inactive in Week 5.

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– WR Treylon Burks

– DL Teair Tart

– LB Luke Gifford

– QB Will Levis 

– OL Jaelyn Duncan

– OLB Caleb Murphy

While not an official inactive, Titans offensive tackle Nicholas Petit-Frere won't play this week despite being reinstated early by the NFL,  Petit-Frere worked on the left side of the offensive line during practice but may need another week to get up to speed in the Titans offense before suiting up for a game.

Prior to this past week, NPF had not practiced with the Titans since training camp.

Defensive lineman Teair Tart's absence could also prove to be significant. With Jonathan Taylor returning and the success Indianapolis has had running the football this season (115.8 yards per game), Tart's presence as a run stopper on Tennessee’s defensive line will be missed.

Wide receiver Treylon Burks will miss his second straight game with a knee injury. Titans head coach Mike Vrabel has said that Burks' current injury is not a reaggravation of his LCL sprain from training camp.

With Burks out, rookie wide receiver Colton Dowell will be active for a second consecutive game after making his NFL debut in Nashville last Sunday. Kyle Philips will also be active for the first time this season.

Derrick Henry looks to continue his reign over the AFC South

King Henry has dominated the division.