Latest injury update could spell disaster for the Bills less than 24 hours after loss against the Dolphins

Not the update fans were hoping to hear.

Adam Zientek NFL News Writer
Add as preferred source on Google
Sep 7, 2025; Orchard Park, New York, USA; Buffalo Bills head coach Sean McDermott reacts during the third quarter against the Baltimore Ravens at Highmark Stadium.
Gregory Fisher-Imagn Images

Injuries are the name of the game for the Buffalo Bills this season. Even before kickoff, several key playmakers were ruled out against Miami. With that, the team activated rookie defensive end Landon Jackson, who went down in pain and was grabbing his knee in the loss. An awful sight with fans fearing the worst.

Jackson has appeared in three games for the Bills after being taken in the third round of the 2025 draft out of Arkansas. The defensive end totaled 16 sacks during his four-year college career.

It’s been reported that Jackson tore his MCL and PCL in Sunday’s loss. Jordan Schultz broke the news on X, formerly known as Twitter. Unfortunately, Jackson’s timeline to return is up in the air. The fan base will need to wait for more information on the injury. Not speculating on injury, but there is a possibility Jackson is lost for the season, depending on the severity of the tear.

Dr. Jesse Morse, a sports medicine physician, broke down what the injury could mean for Jackson on Schultz’s initial post.

“If the MCL is mild (grade 1) or moderate (grade 2) then no surgery is recommended,” Morse wrote. “If the PCL is mild (grade 1) or moderate (grade 2) then no surgery is recommended. If either MCL or PCL is fully torn (grade 3), then he needs season-ending surgery.”

Injuries piling up on both sides of the football

Jackson’s injury forced the team to slide over defensive tackle DaQuan Jones to the defensive end position, as they only had three remaining defensive ends on the roster. Injuries are inevitable, but it feels like Buffalo has been hit especially hard.

Outside of Jackson, the team lost defensive end Michael Hoecht for the season, along with defensive tackle Ed Oliver, who is not expected to return until at least the playoffs.

For Bills Mafia, it’s another gut punch in a season that’s already felt cursed by injuries. All eyes now turn to general manager Brandon Beane and head coach Sean McDermott to see how they patch yet another hole in an already depleted defensive front.