San Francisco 49ers give Brock Purdy a new best friend, completely overhaul the defense during latest 2026 NFL mock draft

The San Francisco 49ers land outstanding haul in latest 2026 NFL mock draft.

Ryan Roberts National College Football Writer
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Clemson Tigers wide receiver T.J. Moore (1) celebrates with Clemson Tigers wide receiver Antonio Williams (0), Clemson Tigers tight end Olsen Patt-Henry (11) and Clemson Tigers wide receiver Tristan Smith (3) after scoring a touchdown Saturday, Nov. 1, 2025, during the NCAA football game against the Duke Blue Devils at Memorial Stadium in Clemson, South Carolina.

When healthy, the San Francisco 49ers are a very good football team. Unfortunately, when it comes to their winning window, the injury bug has plagued them quite a bit over the last couple of seasons. As long as head coach Kyle Shanahan is leading this organization and Brock Purdy is the quarterback, they have a chance. 

In order to preserve their winning window as long as possible, continuing to fill holes on the roster is paramount. General manager John Lynch did just that in this recent 2026 NFL mock draft at A to Z Sports. The two areas of focus was adding support around Purdy and adding difference makers to the defense. 

Round 1, Pick 23: Mansoor Delane, CB, LSU

Delane was a good player while a part of the Virginia Tech program, but he has been a stellar one for LSU this season. While his physical profile is a bit different, there are some parallels to Jaire Alexander. Delane is a diverse cornerback who can play either on the outside or in the slot on the next level. 

Round 2, Pick 54: Isaiah World, OT, Oregon 

The former Nevada transfer has every tool you could want at the offensive tackle position. He is long, explosive, and quick, the building blocks to become a starting left or right tackle on the next level. If the game begins to slow down more for him, World could contribute early on in his career. 

Round 3, Pick 87: Antonio Williams, WR, Clemson 

While Williams isn’t the biggest wide receiver at around 5-11 and 190 pounds, he is a very savvy football player who always seems to get open. Williams works mostly out of the slot for Clemson, and he makes a ton of plays in that role. There are going to be wide receivers in this class that are bigger and faster than Williams, but there aren’t many better football players. 

Round 4, Pick 122: Tyreak Sapp, EDGE, Florida 

Sapp is an explosive defensive end who wins with his combination of power and effort. At around 270 pounds, he has the tools to be a major asset in the run game, as well as reduce down in various alignments as a pass rusher. If nothing else, Sapp is a solid depth piece to an EDGE room. 

Round 4, Pick 138: Marlin Klein, TE, Michigan 

Originally from Germany, Klein is a talented athlete who is still just tapping into his overall ceiling. He got off to a fast start in 2025, but unfortunately, an injury derailed his ascension. There are still a ton of athletic gifts to work with at 6-6 and 250 pounds. 

Round 4, Pick 139: Tim Keenan III, DT, Alabama 

There is nothing fancy about Keenan, but he does all of the dirty work you need on the interior of a defense. He is incredibly strong and is rarely ever uprooted in the running game. There is very little upside as a pass rusher, but Keenan’s role is still very important. 

Round 4, Pick 140: Landed Barton, LB, Utah

Barton is a bigger linebacker with the length and range to play in pursuit, but the pure size to play well against the inside run as well. The versatility that Barton brings is very appealing, and he should also be a notable special teamer if that’s the role you ask of him. 

Round 6, Pick 196: Braelin Moore, OC, LSU 

The former Virginia Tech standout is a great fit in an outside zone running scheme, utilizing his clean movement skills. For a smaller center, he also battles well and has a solid anchor overall. His size at times, however, can cause him some issues against bigger interior defensive linemen.