The 4-5 Seattle Seahawks travel to San Francisco to take on the 5-4 49ers in a crucial Week 11 NFC West matchup. 

The Seahawks will enter this game well rested after a much needed bye week, having lost five of their last six games. Fortunately, they trail the NFC West leading Arizona Cardinals by just 1.5 games. However, the Los Angeles Rams and 49ers are all ahead of Seattle, so it needs to get on track immediately. The Seahawks' offense ranks first in the NFL in passing and ninth overall.

The 49ers gutted out a tough 23-20 victory over the Tampa Bay Buccaneers last week. San Francisco is getting healthy at the right time as running back Christian McCaffrey and receiver Deebo Samuel returned have both returned to action. The 49ers are a well rounded team, ranking second in total offense and ninth in overall defense.

Let's dive into the best odds and bets for this matchup.

*Odds from FanDuel and subject to change

49ers vs. Seahawks Moneyline

49ers: -300
Seahawks: +245

This is the time of year the 49ers kick things into gear. They know how to win when it matters the most, and having McCaffrey back makes a world of difference. They'll miss receiver Brandon Aiyuk a bit, but they have some depth there.

The Seahawks don't do much of anything well on defense, and although they have the top ranked passing offense, the Niners have a very good secondary. Marching into San Francisco and getting a win will take a near perfect effort by Seattle, which I don't think it can do.

49ers vs. Seahawks Spread

49ers: -6.5 (-112)
Seahawks: +6.5 (-108)

The Seahawks may keep it close through three quarters, but I think S.F. pulls away in the fourth. Bet the Niners to cover the spread.

49ers vs. Seahawks Over-Under 48.5 total points

Over: -106
Under: -114

The strength of both these teams are the offenses. Even with the Niners covering the spread, I think both will score enough to get over 50 total points. Bet the over.