The San Francisco 49ers travel to Green Bay to take on the Packers in a huge NFC showdown with playoff implications.

Check out our full odds, picks and predictions for this matchup. Now, here are our best prop bets for Packers vs. 49ers.

*Odds subject to change

49ers TE George Kittle OVER 45.5 receiving yards (-117) – Caesars Sportsbook

Kittle will make his return for this game from a hamstring injury that kept him out last week. He has been the 49ers' most reliable target, leading the team in receptions and touchdowns.

Kittle ranks second among all tight ends in receiving yards, and has eclipsed 45 yards in every game but one this season. The Packers' defense is middling against the pass, so Kittle shouldn't have trouble producing.

Packers QB Jordan Love UNDER 1.5 passing touchdowns (+110) – BetMGM 

It's been a rough go for Love over his last four games, throwing five interceptions and just four touchdowns during that span. In two of those games he was held without a single passing touchdown.

The Packers are a run-first offense with Josh Jacobs, and don't have a clear-cut No. 1 receiver. Love also has a tough matchup this week against a 49ers defense that ranks eighth against the pass.

49ers RB Christian McCaffrey ANYTIME touchdown (-170) – FanDuel

McCaffrey is getting his legs back under him, jumping from 39 rushing yards two weeks ago to 79 yards last week. He didn't find the endzone in either game, but he can only be held out for so long.

In 2023 McCaffrey scored 14 rushing touchdowns and an additional seven receiving. His touches and production should only continue to increase, and the Packers have a middling rush defense.

Packers RB Josh Jacobs OVER 70.5 rushing yards (-115) – BetMGM

Jacobs is the centerpiece of the Packers' offense. He ranks third among all running backs in rushing yards with 838 as well as rushing attempts with 176. Jacobs has eclipsed 70 yards in seven games this season, including in his last four games.

San Francisco has been pretty solid against the run, but Green Bay is going to get yards somehow, and Jacobs is nearly matchup proof at this point.