Bills vs. Chiefs odds, predictions, picks and best bets

The 9-0 Kansas City Chiefs travel to Buffalo to take on the 8-2 Bills in a game that will be crucial in determining the No. 1 seed in the AFC. The Chiefs are coming off a thrilling victory over the Broncos in which they blocked what would have been the game-winning field for Denver goal […]

Nick Roesch NFL Trending News Writer
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Buffalo Bills quarterback Josh Allen (17) is caught from behind by Kansas City Chiefs defensive tackle Chris Jones (95).
© Jamie Germano/Rochester Democrat and Chronicle / USA TODAY NETWORK

The 9-0 Kansas City Chiefs travel to Buffalo to take on the 8-2 Bills in a game that will be crucial in determining the No. 1 seed in the AFC.

The Chiefs are coming off a thrilling victory over the Broncos in which they blocked what would have been the game-winning field for Denver goal as time expired. It seems as though Kansas City continually creates new ways to win, demoralizing its opponents. The Chiefs rank in the top 10 of the NFL in both total offense and defense, and have allowed the least amount of rushing yards to running backs in the league.

The Bills have won five in a row and have a whopping 4.5 game lead in the AFC East. Their 29 points per game average is good for third best in the NFL. Quarterback Josh Allen is having another Pro Bowl caliber season with 2,281 passing yards, 261 rushing yards and 21 total touchdowns. He and running back James Cook make up one of the most dynamic rushing duo's in the league.

Check out the odds and best bets for this matchup.

*Odds from DraftKings and subject to change

Bills vs. Chiefs Moneyline

Bills: -130
Chiefs: +110

This has been the premiere rivalry in the NFL for the better part of the last five years. Every game comes down to the wire and is decided by the little things. While the Chiefs know how to close out games better than anyone, they make a lot of costly mistakes offensively. In a game of this magnitude, mistakes are often what decides who the winner will be.

Kansas City's offense can't be trusted to play a clean a game, and the Bills have the second-fewest turnovers in the NFL with just six. Buffalo actually owns the Chiefs in the regular season, beating them the last each of the last three years, while K.C. returns the favor in the postseason. I'm taking the Bills and betting the moneyline.

Bills vs. Chiefs Spread

Bills: -2.5 (-108)
Chiefs: +2.5 (-112)

This is always an unpredictable matchup, so I'm playing it safe and avoiding the spread.

Bill vs. Chiefs Over-Under 45.5 total points

Over: -112
Under: -108

Two strong defenses that both rank in the top 10 in points allowed should lead the way in a grind-it-out type of game. I'm betting the under.