The 2023 NFL season wasted no time providing football fans with plenty of entertainment, as Week 1 was a positively wild one. It kicked off with Detroit going on the road to defeat Kansas City 21-20 and it ended with the Jets beating Buffalo 22-16 in an overtime thriller that saw New York quarterback Aaron Rodgers go down with a season-ending Achilles’ injury just four games into his tenure with his new team. In between Miami won a 36-34 shootout against the Chargers, San Francisco looked great in a 30-7 rout of Pittsburgh and Dallas humiliated the Giants 40-0.

What will be in store for Week 2? Our experts have broken down the odds and are ready to deliver their favorite NFL picks against the spread.

NFL AGAINST THE SPREAD PREDICTION: Minnesota Vikings +7.5 over Philadelphia Eagles (-115 at PointsBet Sportsbook)

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NFL Expert Picks & Best Bets Against the Spread for Week 2

Our experts have multiple NFL picks against the spread for this week and one of them is for the Vikings to cover against the Eagles on Thursday Night Football. Minnesota is a +7.5 underdog (-115), making Philadelphia a -7.5 favorite (-105). That means an $11.50 bet on the Vikings is successful and returns $10 of profit if they either win outright or lose by no more than seven points. A $10.50 wager on the Eagles gets you $10 in winnings if they prevail by at least eight points.

You have to assume that the Vikings will turn in an inspired performance following a disappointing loss to the Buccaneers in Week 1. Perhaps an underdog role will serve them well after they lost as favorites at the hands of a rebuilding Tampa Bay squad. As usual, Minnesota’s passing attack was effective – with 369 yards, 150 of which went to Justin Jefferson. Now Kirk Cousins and company face a Philadelphia defense that watched Patriots quarterback Mac Jones go for 316 yards and three touchdowns. The Eagles hardly dominated that contest and will probably struggle to put away the Vikings, too. As such, our NFL best bets against the spread include Vikings +7.5

NFL ATS Predictions for Week 2

If you want more NFL picks against the spread, you have come to the right place. Our experts also like the Dolphins to cover a -2.5 number against the Patriots.

With the Bills having turned in a poor performance on Monday Night Football and the Jets now without Rodgers for the season, the Dolphins may be the cream of the crop in the AFC East. They opened with a bang this past weekend, going into Los Angeles and beating the Chargers 36-34. Tua Tagovailoa threw for 466 yards and three touchdowns, while Tyreek Hill finished with 11 receptions for 215 yards and two scores. Although New England’s offense fared decently against Philadelphia in Week 1, it’s not the kind of attack that is built to win high-scoring affairs – and it looks like that is required against Miami.

Therefore our NFL ATS picks include the Dolphins winning by at least a field goal.

Make sure you're making your NFL picks against the spread with PointsBet and you can do so by clicking right here to get the ball rolling.

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You can secure a unique PointsBet promo with a guaranteed $150 value when you either fade or follow any of our NFL picks against the spread. As you will see below, the process could not be any easier:

1. Sign up here for a new PointsBet account
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Yes, it really is that simple. That’s all it takes to receive $150 off Fanatics.com gear, as you unlock the generous offer even if $50+ first bet loses! This is a great way to represent your favorite team out in public during football season. Now that the festivities on the gridiron are underway, there has never been a better time to become a new member at PointsBet and wager on our NFL expert picks against the spread.

Full List of NFL Spreads for Week 2

In order to make the best possible NFL picks against the spread, it is important to know all of the lines for the entirety of this week’s action. Here the odds, starting with Vikings at Eagles for Thursday Night Football and going through a pair of Monday Night Football games:

• Minnesota Vikings +7 (-115) vs. Philadelphia Eagles – Thursday, September 14
• Kansas City Chiefs -3 (-110) vs. Jacksonville Jaguars – Sunday, September 17
• Las Vegas Raiders +8.5 (-108) vs. Buffalo Bills – Sunday, September 17
• Seattle Seahawks +5.5 (-112) vs. Detroit Lions – Sunday, September 17
• Los Angeles Chargers -3 (-115) vs. Tennessee Titans – Sunday, September 17
• Baltimore Ravens +3 (-102) vs. Cincinnati Bengals – Sunday, September 17
• Chicago Bears +3 (-110) vs. Tampa Bay Buccaneers – Sunday, September 17
• Green Bay Packers -1 (-112) vs. Atlanta Falcons – Sunday, September 17
• Indianapolis Colts -1.5 (-112) vs. Houston Texans – Sunday, September 17
• San Francisco 49ers -8 (-110) vs. Los Angeles Rams – Sunday, September 17
• New York Giants -5 (-110) vs. Arizona Cardinals – Sunday, September 17
• New York Jets +9 (-112) vs. Dallas Cowboys – Sunday, September 17
• Washington Commanders +3.5 (-115) vs. Denver Broncos – Sunday, September 17
• Miami Dolphins -2.5 (-115) vs. New England Patriots – Sunday, September 17
• New Orleans Saints -3.5 (-105) vs. Carolina Panthers – Monday, September 18
• Cleveland Browns -2 (-110) vs. Pittsburgh Steelers – Monday September, 18

Remember, you can bet on any of these games – not just our NFL ATS picks – and secure the PointsBet $150 promo by activating our link before kickoff.

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