Nearly each week in the NFL features an upset. As we enter the second half of the regular season, teams begin to raise their game as the stakes keep getting higher. Here are our underdog picks that could win outright in Week 10.

*Odds subject to change

Pittsburgh Steelers OVER Washington Commanders (+126 moneyline) – FanDuel

Six of the Commanders' seven wins this season have been against teams with losing records. Rookie quarterback Jayden Daniels and the Washington offense hasn't faced a defense the caliber of the Steelers, which is allowing the third-lowest amount of points per game.

This should be a close game, but I think Pittsburgh's defense contains the Commanders' offense. The Steelers play clean and efficiently on offense, and their eighth ranked rushing attack is a mismatch for Washington's 29th ranked run defense.

Arizona Cardinals OVER New York Jets (+110 moneyline) – DraftKings

The Cardinals are quietly one of the hottest teams in the NFL, winners of their last three games. They have a lot to play for as they hold a slim lead for first place in the NFC West.

The Jets, meanwhile, lost five games in a row before finally getting a win last week over a decimated Houston Texans team. Arizona's offense has averaged 25 points per game during their winning streak, while New York has averaged just 19 points per game during that stretch.

Tampa Bay Buccaneers OVER San Francisco 49ers (+235 moneyline) – Caesars Sportsbook

The Buccaneers still have a lot to play for as they trail the Atlanta Falcons by just two games in the NFC South. Despite being hit hard by injuries, Tampa Bay took the undefeated Kansas City Chiefs to the limit last week, falling just short of a victory in overtime.

Quarterback Baker Mayfield is playing the best football of his career, and he has an excellent rushing attack behind him with the duo of Rachaad White and Bucky Irving. As for the 49ers, they are dealing with multiple injuries of their own and haven't strung together back-to-back wins once this season.