Nearly each week in the NFL features an upset. As we enter the stretch run of the regular season, struggling teams begin to raise their game as the stakes keep getting higher, and top teams let their guard down.

Here are our underdog picks that could win outright in Week 14.

*Odds subject to change

Seattle Seahawks OVER Arizona Cardinals (+120 moneyline) – FanDuel

It's been difficult to know what to expect from each of these teams this season. They've both overachieved at times, as well as underachieved, and have been very hot or cold. Their team rankings are nearly identical, as Arizona ranks 17th in total defense and Seattle ranks 18th. The Cardinals have the No. 11 overall offense in the NFL, and the Seahawks come in at No. 16.

Despite Arizona ranking a little higher in most categories, it's struggling to close out games. Seattle has the firepower offensively to to seal the deal in the fourth quarter, and has actually played better on the road than at home this season with a 4-1 record. This should be a tight matchup, but I think the Seahawks are more talented, and I trust them more.

Jacksonville Jaguars OVER Tennessee Titans (+165 moneyline) – BetMGM

This is a matchup of two of the worst teams in the NFL, so anything can happen. The Titans got blown out by the Washington Commanders last week by a score of 42-19 in which they weren't even remotely competitive. The Jaguars are riding a five-game losing streak, but have played hard as four of those five losses came by just one score.

Backup quarterback Mac Jones will get the start for the injured Trevor Lawrence in this game, and Jones played well last week, throwing for 235 yards and two touchdowns. This should be a close game that could go either way.

Chicago Bears OVER San Francisco 49ers (+176 moneyline) – FanDuel

The Bears have a new head coach in Thomas Brown following the firing of Matt Eberflus last week. Teams are often rejuvenated after changing coaches and elevate their play. Brown will bring a run-heavy approach on offense, which matches up well against the 49ers' 26th ranked rushing defense.

Four of Chicago's last six losses have been by just one possession. As for San Francisco, it suffered a big blow having to place star running back Christian McCaffrey on injured reserve. The 49ers are having a hugely disappointing season at 5-7, and could be entering this matchup with low morale.