The San Francisco 49ers return from the bye in Week 10 looking to end a three-game losing streak in a tough road matchup with the Jacksonville Jaguars.

Despite a damaging slump that has dropped them to 5-3, the 49ers can pull to within two games of the Philadelphia Eagles in the race for the No. 1 seed in the NFC with a victory over 6-2 Jacksonville.

It is an extremely compelling game stuffed with intriguing storylines. Brock Purdy will be out to shake off a spate of costly recent turnovers against the third-ranked defense by Expected Points Added per play and will have Deebo Samuel back to help. On defense, it will be the 49ers debut for Chase Young, the former second overall pick whom San Francisco landed in a blockbuster trade deadline deal.

Young joins a 49ers pass rush surprisingly struggling to convert pressures into sacks. Facing one of the NFL's best young quarterbacks in Trevor Lawrence, the onus will be on the 2020 Defensive Rookie of the Year to make an immediate impact and help ease the scrutiny on coordinator Steve Wilks.

Given the raft of narratives at play and the two teams' prominence in the playoff picture, it is no surprise that, though it is technically not America's Game of The Week, most of the national audience on Fox will see 49ers at Jaguars.

Will you have the opportunity to watch on TV? If you live in any of the red areas on the below map, you will be able to watch the game on Fox during the 1 p.m. ET slot.

The New Orleans Saints' road game with the Minnesota Vikings will be seen in New Orleans and Atlanta as well as large parts of the midwest.

Fox will show an all-AFC North matchup between the Baltimore Ravens and Cleveland Browns that will air in both those markets as well as Kansas City and much of Pennsylvania, though Eagles fans enjoying their team's bye week will get the chance to see if one of their nearest rivals can arrest the slide.

First 49ers injury report for Week 10, at Jaguars

There’s doubt over a critical offensive starter.