Nearly each week in the NFL features an upset. As we enter the second half of the regular season, struggling teams begin to raise their game as the stakes keep getting higher, and top teams let their guard down.

Here are our underdog picks that could win outright in Week 12.

*Odds subject to change

Arizona Cardinals OVER Seattle Seahawks (-110 moneyline) – BetMGM

This game should be extremely tight, as evident by the one-point spread in favor of Seattle. The similarities in statistical rankings between these two teams on both sides of the ball are staggering, ranking within three spots of each other offensively and just one spot defensively. 

You might be inclined to give the Seahawks the edge playing in Seattle, but they are actually 2-4 at home this season. I'm going to give the edge to the Cardinals, who have been just a tad more consistent throughout the first 10 games.

San Francisco 49ers OVER Green Bay Packers (+120 moneyline) – DraftKings

This should be another tightly contested matchup in Week 12. Both teams tend to play close games and are a bit unpredictable. The 49ers rank highly in most team stat categories, but are letting games slip away late. I have to believe that they are too talented to keep losing in that fashion, especially considering their history in big games.

Tight end George Kittle is expected to return for this game, and he makes a huge difference in S.F.'s passing game. Packers quarterback Jordan Love has been inconsistent and a bit reckless throwing the ball this season, which is dangerous against a very good 49ers secondary. I think the Niners take care of the ball and makes a couple more plays than Green Bay to secure a win.

Chicago Bears OVER Minnesota Vikings (+162 moneyline) – Caesars Sportsbook

The Vikings have been eking by some weak opponents lately and have lost some explosiveness on offense that they had earlier in the season. Quarterback Sam Darnold has come back down to Earth after a hot start, throwing five interceptions over his last three games.

The Bears gutted out a tough win over a good Green Bay Packers team last week. At 4-6, they are desperate to save their season and get back into the playoff picture. Chicago's stingy defense is allowing just 19 points per game and has forced the fourth-most turnovers in the league.